ENGINEERING PROJECT SUMMARIES
SPRING 2025
Gabriel Rodriguez Rivera
Chemical Engineering
College of Engineering
The objective will be to enhance the printer by making it a multi-material printer, with two to three extruders.
Problem: The advancements of 3D printers have been a valuable tool for tissue engineering (TE). TE combines scaffold fabrication, chemical cues and cells to study, treat, or restore tissue function. 3D printing can control spatial differences to mimic the 3D structure of a tissue better. Commercial low-cost extrusion printers are limited to commercial inks and are unsuitable for biological applications. On the other hand, commercial bioprinters used for this purpose could range from $10,000 to $200,000. The high cost of these printers limits their use in research.
Opportunity: Affordable 3D printers have the potential to revolutionize scientific research by making advanced additive manufacturing accessible to more laboratories. The expiration of key patents has fueled the rise of open-source, low-cost 3D printing solutions, enabling researchers to fabricate custom tools and prototypes. While traditional thermoplastics limit bioprinting applications, affordable extrusion-based adaptations offer a cost-effective way to develop biocompatible tissue scaffolds. By leveraging existing 3D motion systems, researchers can construct reliable bioprinters without extensive hardware expertise. This democratization of bioprinting technology empowers innovation, particularly in resource-constrained settings, fostering new biomedical and tissue engineering advancements.
In addition to Dr. Rodriguez Rivera, the student will be paired with a senior undergraduate student and will work on completing different milestones over the 10 weeks. Students will use the open resources to build, validate, and test an .
Built: Students must be familiar with or willing to learn any computer-aided design program. For this design project, some parts might be commercially available, and others will be 3D printed using extrusion printers available at Villanova.
Validate: The Team will test the printability of the printers and replicate previous results with single materials.
Apply: For the last part of their project, the students will learn the fabrication techniques for granular hydrogels. Finally, they will use the 3D printer they built to print granular hydrogel scaffolds for tissue applications. Students must incorporate the knowledge acquired, building and testing the 3D printer, with information from the literature, to determine optimal parameters to successfully 3D print the granular scaffolds. They will also get experience writing the protocol for operating the custom-made 3D printer.
Innovation:
- The team will prepare a multi-material 3D printer
- The team will assess a continuous microgels fabrication using the 3D printer
Jacob Elmer
Chemical Engineering
College of Engineering
The main goal of the Elmer lab is to develop safe, effective, and inexpensive gene delivery methods for human gene therapy treatments. Specifically, we try to optimize the sequence of the gene and the upstream promoter that drives transcription. While we have had success tweaking the sequence of commonly used promoters to increase their activity, the student involved in this project will be challenged with the task of building a promoter from the ground up to obtain a promoter sequence that is as compact as possible while providing levels of gene expression that are similar to other large and powerful promoters (e.g., CMV, EF1alpha, et al.). This will require the student to familiarize themselves with fundamental genetics (e.g., what does it take to recruit RNAPII to a promoter?) and cutting-edge literature on the activity and binding sites of transcription factors that can boost transcription levels. The result of this work will be a minimal promoter that can be used to improve a wide variety of gene therapy treatments, since previous studies have clearly shown that it is easier to efficiently deliver a smaller gene expression cassette (i.e., promoter + gene + polyA termination signal) than a larger one.
Note: Many of the experiments involved in this project are flexible and can happen at any time, but working with human cells requires a relatively rigid schedule that the student must be able to follow. Specifically, a given week will require the following time commitments:
Monday: 1-2 hours to passage cells
Tuesday: 1-2 hours to deliver the plasmids to the cells (must be 24 hours after activities on Monday)
Thursday: 1-2 hours to analyze gene expression patterns
These events may also be shifted forward one day in the week, if necessary (e.g., Tuesday, Wednesday, and Friday).
The student involved in this project will be trained in the following methods:
- Manufacturing of (minicircle) plasmid DNA via bacterial cell culture and minipreps
- Molecular genetics techniques like PCR and Gibson Assembly are used to change the sequence of a plasmid or promoter
- Animal cell culture techniques that will be used to grow human cells for testing
- A variety of gene delivery techniques, including electroporation and lipofection, are used to deliver the (minicircle) plasmids into human cells
- Fluorescent microscopy and flow cytometry are used to measure how many of the cells express a given gene (e.g., GFP) and at what level. These techniques will be essential for comparing the promoter that is designed by the student to other commonly used strong promoters.
Furthermore, this student will join a team of other researchers, including a PhD student and a senior undergraduate student researcher. The team will meet weekly with Dr. Elmer to discuss progress, troubleshoot experiments, and plan next steps.
Arash Tavakoli
Deeksha Seth
Stephen McGill
Nathan Chodosh
Civil and Environmental Engineering, Mechanical Engineering
College of Engineering
This project focuses on developing the software “brain” for an F1/10 autonomous racing car. The student will work on algorithms for computer vision, perception, and decision-making, enabling the car to sense its environment and navigate a track at speed. Tasks may include implementing camera-based lane detection, fusing sensor data for localization, and optimizing control strategies for racing performance.
The project is highly hands-on, combining AI, robotics, and real-time programming in a multidisciplinary setting. By joining this effort, the student will gain experience in cutting-edge autonomy technologies, contribute to Villanova’s first F1/10 racing platform, and help prepare the team for participation in the international F1/10 racing competition at ICRA.
Specific responsibilities include:
- Developing and testing computer vision algorithms for lane detection, obstacle recognition, and track following.
- Implementing real-time control software to integrate perception, planning, and actuation on the vehicle.
- Working with sensors (e.g., cameras, LiDAR, IMU) and fusing data to improve localization and navigation accuracy.
- Collaborating with faculty and student team members in Mechanical and Civil Engineering to ensure smooth integration of hardware and software systems.
- Preparing code, documentation, and preliminary results that will contribute to Villanova’s submission for the ICRA F1/10 autonomous racing competition.
Skills Students Will Gain: through this project, the student will develop:
- Hands-on experience in computer vision, AI, and robotics software development.
- Proficiency in Python and/or C++ programming for robotics applications.
- Knowledge of ROS (Robot Operating System) and other standard tools for autonomous systems.
- Practical skills in sensor integration and real-time control systems.
- Experience working in a multidisciplinary team, building collaboration skills across engineering fields.
- A deeper understanding of how AI methods translate into real-world autonomous systems.
Arash Tavakoli
Civil and Environmental Engineering
College of Engineering
This project focuses on the development of an iOS application designed to support experience sampling methodology (ESM), a widely used approach for capturing real-time data on human behavior, cognition, and emotional states. The app will allow researchers to design and deploy flexible surveys and prompts that can be delivered to participants at random or scheduled intervals throughout the day. Participants will be able to respond directly on their smartphones, enabling the collection of ecologically valid, time-sensitive data in natural environments. Key features of the app will include customizable survey templates, integration of branching logic, and support for multimedia questions (e.g., image or audio responses). The platform will also incorporate secure data storage and user-friendly dashboards to facilitate real-time monitoring of participation and response rates. Additionally, the app will be designed with scalability in mind, allowing it to adapt across multiple research domains such as psychology, transportation, and public health. By developing this tool, the project aims to reduce reliance on paper-based or delayed self-report methods and provide a more accurate, efficient, and user-centered system for collecting in-the-moment experiences. The outcome will be a flexible and extensible iOS app that enhances research capabilities across diverse fields of study.
The first-year Match research assistant will contribute to the initial development of an iOS application designed to support experience sampling research. In the first phase, the student will focus on creating a simple prototype app capable of sending randomized notifications to users throughout the day and recording basic responses (e.g., How was your day today on a scale from terrible to very good?). In addition to meeting regularly with Dr. Tavakoli, the student will then work alongside a PhD researcher to expand the app’s functionality, including features such as data storage, user interface refinement, and potential integration with backend services. Depending on the student’s interests, there may also be opportunities to contribute to usability testing and human-centered design aspects of the app.
Through this project, the student will gain hands-on experience with Swift and iOS frameworks (SwiftUI or UIKit), app prototyping, and the fundamentals of backend communication and database management (e.g., Firebase, Core Data). They will also develop problem-solving, project documentation, and collaborative research skills while engaging in the lifecycle of app development. This position is designed to provide a foundation for continued work beyond the semester, with opportunities for deeper involvement in applied research on human-technology interaction, in case the applicant is interested.
Wenqing Xu
Civil and Environmental Engineering
College of Engineering
Rapid quantification of multi-per per- and polyfluoroalkyl substances (PFAS) at sub-ng·L⁻¹ concentrations in water remains a critical technological challenge. PFAS, nicknamed "forever chemicals" because they don't break down naturally, can build up in our bodies and the environment over time. They're found in everything from non-stick pans to firefighting foam, and they're increasingly showing up in our drinking water. This project aims to develop a portable and highly adaptable sensor platform for rapid electrochemical detection of multiple PFAS at sub-ng L-1 concentrations. Four tasks are proposed to achieve this goal: (1) synthesize conductive and redox-active MIPs for individual PFAS, (2) select the best-performing MIP for individual PFAS with the highest selectivity and sensitivity, (3) assemble an MIP-microelectrode array for simultaneous quantification of multiple PFAS, (4) assess sensor performance and perform techno-economic analysis. This proposed work leverages the novel PFAS sensing mechanism discovered by PI Xu for direct electrochemical quantification, which enables the miniaturization of the developed sensor platform and opens up the possibility of continuous monitoring.
The participant will assist a PhD student in conducting the proposed research activities. Students will gain hands-on experience in cutting-edge environmental chemistry and engineering. Students will learn fundamental principles of electrochemistry by working with specialized sensors that detect electrical changes when target molecules bind to designed materials. They'll develop laboratory skills in creating molecularly imprinted polymers (MIPs), which are custom-made materials with molecular-sized holes that act like "locks" for specific PFAS "keys." They'll work with real environmental samples, learning how laboratory discoveries translate to solving actual water contamination problems. The project introduces students to interdisciplinary problem-solving, combining chemistry, materials science, and environmental engineering.
David Burnett
Electrical and Computer Engineering
College of Engineering
In extremely crowded environments with thousands of wireless devices, we have often observed wireless links become unreliable: Wi-Fi operates slowly, intermittently, or can't connect entirely. We assume the wireless channel is clogged with transmissions, and there is no hope of communication. However, we have recorded a large set of wireless spectrum data in such a crowded environment and found that much of the 2.4 GHz spectrum is empty, even when Wi-Fi is unusable! This indicates we can design intelligent algorithms to identify narrow slices of bandwidth and time during which communication can be successful, despite the apparent clogging of Wi-Fi communication. Furthermore, we have recordings of other environments we can analyze for comparison, including a convention presentation hall with thousands of people in attendance, a room with approximately 10 virtual reality and other gaming systems causing wireless interference, and a traditional office environment with approximately 10 occupants using ordinary Wi-Fi-enabled laptops.
In this project, the student will first analyze existing data, looking for gaps in the spectrum that present narrowband communication opportunities. The goal will be to confirm the hypothesis that ample spectrum exists for low-latency wireless communication of approximately 5 MHz bandwidth at most, or any time during the spectral recordings. We will also examine salient differences in the spectrum usage between recordings.
We will then propose and test algorithms to determine which wireless channel to communicate on at what time, and which channel to switch to in case of a collision, to maximize throughput and minimize packet transmission retries. Near the conclusion of the project, we will write up the results for publication at a suitable wireless communications conference or peer-reviewed journal.
Advanced students will have the opportunity to use new observation hardware platforms we will purchase as needed. This project is intended to grow and, in the future, implement developed algorithms on a real radio system and test it in a high-interference environment.
This project is designed to get a student up and running on new research work fast by providing a pre-collected data set for analysis. Analysis can be performed using many different types of software and the project can be tuned based on what the student is experienced with or wants to gain experience with. Jupyter notebook or Matlab are preferred.
The student will be expected to first create 3D (2D+color) plots of data based on existing scripts that will be provided, and examine the data graphically to explore regions of the spectrum and time that are quiet enough to support communication. They will next be responsible for proposing simple rules, heuristics, neural networks, or other algorithms for a hypothetical wireless transmitter. This transmitter will use recent observations (failed transmission statistics, observed energy levels while listening, etc.) and past information (observed trends over several hours or days) to predict which wireless channel to use next.
In addition to data analysis, this project will educate the student in the basics of radio receivers, wireless channel noise and interference, wireless embedded systems, and preparing academic publications. The student will likely work with both Dr. Burnett and 1-2 of his graduate students on an ad hoc basis and during weekly research group meetings, during which all students are expected to report their recent results.
Jiafeng Xie
Electrical and Computer Engineering
College of Engineering
Post-quantum cryptography (PQC) is a new type of cryptosystem that is resistant to the attacks launched by mature quantum computers. The 2022 U.S. National Security Memorandum emphasized that the U.S. must transition to PQC by 2035. Meanwhile, several PQC algorithms have been proposed for potential standardization under the National Institute of Standards and Technology (NIST) standardization process. More importantly, the recent advancement in the field involves determining the implementation performance of a PQC algorithm on a hardware platform.
In this project, we follow this trend to conduct research on efficient hardware acceleration of a PQC algorithm that is already selected for standardization by NIST, the lattice-based cryptography Kyber (also named as ML-KEM). We have identified that one of the most complicated arithmetic operations for ML-KEM is the polynomial multiplication over a ring. Hence, in this project, we will: (i) train and equip the supported undergraduate research student with the required hardware skills for implementing this polynomial multiplication (Project Mentor and the student will study the mathematical background together); (ii) learn the hardware design language coding skills and hardware design techniques to design the targeted operations into efficient hardware architectures, along with testing and evaluation; (iii) explore possible optimization techniques to improve the hardware accelerator’s final implementation performance.
This project will be led by Dr. Jiafeng Harvest Xie from the Electrical and Computer Engineering Department and the whole project will last for 10 weeks, with 10 hours per week. The Project Mentor will advise the supported student to conduct the research proposed above. A complete version of the polynomial multiplication accelerator for ML-KEM is expected to be achieved by the end of the project. The results obtained from this project will be documented and compiled into a paper for possible publication in an IEEE Conference or even a Journal.
The Security and Cryptography (SAC) Lab of the Department of Electrical and Computer Engineering, led by Dr. Jiafeng Harvest Xie, is seeking one undergraduate research assistant under the support of the Villanova Match Program project -- Efficient Hardware Acceleration of Number Theoretic Transform for NIST-Selected Post-Quantum Cryptography Scheme ML-KEM.
Basic requirements: knowledge of computer design and programming languages such as Python; prior experience in hardware design will be desirable.
Period: Spring 2026 (10 weeks). Working time is around 10 hours per week at $10/hour. The project is open to all interested applicants.
Results: It is expected that by the end of the project time, the student will be familiar with and handle hardware design languages and tools like VHDL/verilog, Quartus Prime, Vivado, and ModelSim. A possible paper will also be submitted for publication based on the obtained results.
Background information: Dr. Xie has been actively involved with quantum-resistant cryptosystem research. He has supervised a successful student project that led to a publication in IEEE Computer Architecture Letters, which was awarded the Brian Anderson Memorial Award (ECE Department) and the prestigious 2022 IEEE Philadelphia Section Merrill Buckley Jr. Student Project Award.
Please feel free to contact Dr. Xie via email.
Deeksha Seth
Mechanical Engineering
College of Engineering
This project centers on the design and development of smart educational technologies in the form of bio-inspired robots. These robots take inspiration from nature, such as the mechanics of a snake’s jaw, a goldfish’s swimming motion, and a starfish’s locomotion, and translate them into engineered systems that demonstrate real scientific and mathematical principles. These robots integrate biology and engineering and support integrative STEM learning - highlighting how nature and engineering connect in the real world.
The research advances two complementary goals. First, it is the technical design of bio-inspired robots that are safe, robust, and engaging, while being practical for use in K–12 classrooms and informal learning environments like museums. Second, it investigates their educational impact, examining how these tools foster cross-disciplinary connections and increase student engagement with STEM concepts. This work is highly collaborative, bringing together teachers, museum educators, and students in iterative cycles of design, testing, feedback, and refinement.
This work highlights how technology interfaces with society. Students gain experience not only in mechanical and robotic system design but also in human-centered problem solving, developing technologies that directly serve learners and educators.
The first-year Match research assistant will support both the technical and research aspects of the bio-inspired robotics project. Responsibilities include:
- CAD modeling and design of mechanical components.
- Prototyping and manufacturing using 3D printing and traditional manufacturing methods
- Electronics and circuits development, including microcontrollers, sensors, and actuators.
- Coding and programming to implement robot functions and controls.
In addition to technical work, the student will assist with the educational research dimension of the project. This includes collecting and analyzing data from classrooms and museums, helping evaluate how the robots function as learning tools, and connecting design decisions to broader social and educational needs.
Through this role, the student will gain:
- Technical skills in mechanical design, prototyping, electronics, and programming.
- Experience with the design–build–test process for robotics.
- Research skills in evaluating technology with users and applying design science methods.
- Communication and collaboration experience in interdisciplinary teams.
Calvin Li
Mechanical Engineering
College of Engineering
Many additive manufacturing materials are metal materials, while the 3D printers for undergraduate experiments and research are based on polymer/plastic materials. The 3D metal printers are often expensive when purchased commercially, making low-cost 3D metal printers is vital to enable many undergraduate research and experiments. This project will give the senior design group an exciting experience of the production and testing of an electrochemical 3D metal printer. The 3D printer can create metallic components based depositing adherent layers of metal ions onto the surface of a conductive substrate. The printing head consists of a sharp-tipped electrode submerged in an electrolyte close to a conductive substrate. Under a positive potential between anode and cathode, metal ions deposit on the conductive substrate as the metal ions are reduced. Meniscus confined electrochemical (MCE) 3D printing is another approach to building metallic structures through the formation of a stabilized liquid meniscus between the dispensing nozzle. The design considerations for a meniscus confined printing approach will have superior print speeds to equivalent works of classical 3D printers, which will require the meniscus diameter of the printing nozzle to be submillimeter size and the integration of a porous sponge into the print head to balance the hydraulic head of the electrolyte. Other piston-based methods of controlling the electrolyte meniscus will be tested, too, for better control. The carbon paste working electrode will be tested in potassium ferricyanide and other metallic solutions for both variable scan rate and concentration responses. In the end, the goal of this low-cost 3D metal printer should demonstrate it can be used in a variety of electrochemical experiments for metal parts printing.
The first-year match research assistant will work with graduate students and Dr. Calvin Li to conduct experiments on a 3D metal printer and refine the design of the metal printer nozzle and program to achieve complex structures that are not possible with conventional machining tools.
Bo Li
Mechanical Engineering
College of Engineering
The goal of this project is to create soft, skin-conformal pressure sensors for next-generation wearable health monitoring. Current commercial patches for electrocardiography (ECG) or pulse tracking are often bulky, stiff, and require strong contact pressure to maintain signal quality, which can cause discomfort or red marks after extended use. These properties limit their potential for long-term and continuous physiological monitoring. Our group has developed a new ultrathin sensor with a thickness down to a few nanometers. This ultrathin dielectric has a low elastic modulus, closely matching the softness of human epidermis and enabling sub-pascal pressure detection. These features allow the sensor to detect subtle pressure changes while remaining gentle and non-invasive on the skin. In this project, we will explore how fabrication conditions such as surface cleanliness, annealing temperature, and dielectric thickness influence signal stability, noise level, and long-term performance. Our goal is to reduce the noise level while preserving the high sensitivity and mechanical compliance of the device. This is a new system for our group and will provide insight into how nanoscale dielectric structures influence signal behavior in soft capacitive electronics. The outcome may also support our ongoing intellectual property development and contribute to broader efforts in soft and wearable electronics for health applications. We hope this project will inspire students to explore the fields of nanomaterials, bio-integrated sensors, and biomedical device engineering.
The undergraduate student’s responsibilities include:
- Prepare nanomaterial dispersions and surface treatment solutions
- Participate in dielectric thin film fabrication using sputtering and photolithography facilities
- Characterize sensor structure and performance using optical microscopy, scanning electron microscopy, and Raman spectroscopy
- Read literature
- Perform data sorting, treatment, plotting and present the results
Bo Li
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College of Engineering
The goal of this project is to advance the development of smart and sustainable sensing technologies for environmental monitoring by creating a novel Raman platform for the detection of per- and polyfluoroalkyl substances (PFAS). PFAS, often referred to as “forever chemicals,” are highly persistent, bioaccumulative, and toxic pollutants that pose serious risks to both human health and ecological systems. Their long-term accumulation in water resources requires highly sensitive and accessible detection methods to ensure safety and sustainability. Currently, liquid chromatography–mass spectrometry (LC-MS/MS) is considered the gold standard for PFAS detection, but its reliance on costly instrumentation and labor-intensive protocols makes it impractical for widespread, routine use. Our team has recently demonstrated that MPRS provides an innovative solution by employing molecular probes that are uniformly distributed on polymer substrates, enabling highly sensitive detection through enhanced molecular interactions. This platform has already achieved a detection limit exceeding the capabilities of LC-MS/MS by four orders of magnitude. In this proposed project, we will build on this success by incorporating novel nanomaterials to further advance the sensitivity and selectivity. We will further investigate sensor fabrication methods, test performance in realistic water samples, and establish scalable procedures for broader application. By enabling rapid, ultratrace, and cost-effective detection of PFAS, this project will contribute directly to environmental protection, public health, and long-term sustainability, while also providing training opportunities that inspire students in the fields of materials science, spectroscopy, and environmental engineering.
The undergraduate student’s responsibilities include:
- Prepare the PFAS solution
- Characterize the samples using an optical microscope, a scanning electron microscope, and a Raman spectrometer.
- Read literature.
- Perform data sorting, treatment, plot and present the results
Qianhong Wu
Mechanical Engineering
College of Engineering
Traumatic brain injury (TBI) is a critical public health issue that affects individuals across all demographics, with particularly high prevalence in sports-related activities. Concussions, the most common form of mild TBI, remain difficult to study due to the complex anatomy of the head. The brain is suspended in cerebrospinal fluid, supported by porous subarachnoid trabeculae, and encased within the opaque skull. This makes direct observation of impact mechanics nearly impossible using conventional imaging or experimental approaches.
To overcome this challenge, our lab has developed a patented biomimetic head surrogate known as Smart Brain Technology. This model replicates the structure of the human head with a hydrogel-based brain and a transparent skull, providing a unique platform to visualize internal responses to external forces. By outfitting the surrogate with pressure and acceleration sensors, we can quantify how forces propagate through brain tissue and identify localized regions of stress or strain during impact.
In this project, we will subject the surrogate to controlled impact experiments designed to mimic real-world collision scenarios common in sports. The data collected will allow us to observe the onset and progression of concussion mechanisms that cannot be directly measured in living subjects.
The insights gained from this study have three major implications: first, improving scientific understanding of how and where brain injuries occur; second, supporting the development of more effective diagnostic and treatment strategies; and third, informing the design of advanced protective equipment, such as helmets, to better safeguard athletes and reduce the risk of long-term neurological damage.
By combining innovative experimental design with cutting-edge biomimetic modeling, this project has the potential to bridge critical gaps in TBI research and contribute to both clinical and preventative advances in brain health.
As a research assistant on this project, the student will work directly with the Smart Brain Technology surrogate system to investigate concussion mechanisms. Specific responsibilities will include contributing to experimental design aimed at improving the surrogate’s biological accuracy, conducting controlled impact tests equipped with pressure and acceleration sensors, and managing data acquisition throughout the testing process. The student will also participate in reviewing, processing, and visualizing the collected data to identify patterns, validate results, and inform future refinements of the model.
Through these activities, the student will gain valuable hands-on experience in engineering experimental design, setup, and analysis. They will develop technical proficiency with widely used engineering and research tools, including SOLIDWORKS for modeling, MATLAB for data analysis, and LabVIEW for instrumentation and control. Beyond software skills, the project will cultivate critical research competencies such as problem-solving, quantitative reasoning, and scientific communication.
By the conclusion of the project, the student will have strengthened both their technical and analytical skill sets, while also gaining practical insight into how engineering approaches can be applied to complex biomedical challenges such as traumatic brain injury.
